نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I
نویسندگان
1 گروه تربیت بدنی و علوم ورزشی، دانشکده تربیت بدنی، دانشگاه صنعتی شاهرود، شاهرود، ایران.
2 گروه فیزیولوژی ورزشی، دانشکده تندرستی و علوم ورزشی، دانشگاه شهید بهشتی، تهران، ایران.
3 گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی، تهران، ایران.
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Aim: The purpose of this study was to investigate the effect of creatine supplementation on malondialdehyde (MDA), glutathione disulfide (GSSG), glutathione (GSH) and the ratio of these two after repeated intensive exercise in wrestlers.
Method: This study utilized a double-blind, placebo-controlled, crossover design. For this purpose, 10 subjects with mean age 22.5±3 years voluntary participated in this study. with subjects participating in both 2 stages of intensive exercise with 15 min Inactive rest. Each stage included three lower and upper extremity Wingate test and with alternative pattern with 1 min active rest between each test. First time creatine or placebo (0.1 gr per kg of body weight) were consumed. Also, the second dose of supplement or placebo was given after the end of second stage of test and third dose was given after the completion of fourth stage. Blood sample was taken before and after and one hour after recovery.
Results: The results of the research using the method of repeated analysis of variance (2x3) showed that the consumption of creatine supplement compared to the placebo prevented the increase in the glutathione disulfide (p=0.008) and malondialdehyde (p=0.001), but the response of the GSH and GSH/GSSG ratio were not related to creatine consumption (p<0.05).
Conclusion: It seems that the creatine supplementation can have a significant effect on some indicators of oxidative stress in wrestlers, but due to the no change in other indicators, further research is suggested.
کلیدواژه‌ها [English]
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