The effect of HIFT with ginger extract supplementation on the levels of some antioxidant enzymes in men with non-alcoholic fatty liver

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran.

2 Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.

3 Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran

4 Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.

Abstract

Aim: This study investigated the combined effect of HIFT and ginger extract on antioxidant enzymes in men with NAFLD.

Methodology: This study was conducted experimentally with a pretest-posttest design. 40 men with nonalcoholic fatty liver disease were randomly assigned to four groups: supplementation, HIFT training, combination of supplementation and training, and placebo. HIFT training, including strength and aerobic exercises, was performed three sessions per week for eight weeks. The supplementation groups consumed 1 g of dry ginger extract daily in four doses. Serum levels of catalase, SOD, GPX, TAC, and MDA were measured.

Results: ANOVA analysis with repeated measures showed that there was a significant difference in the levels of TAC, CAT, GPX, and SOD enzymes in the groups of the present study (p<0.05), so that in the supplement, exercise, and supplement + exercise groups, the levels of TAC, CAT, GPX, and SOD enzymes increased significantly in the post-test compared to the pre-test (P ≥0.05). While MDA levels decreased significantly in the aforementioned groups (P ≥0.05).

Conclusion: In summary, it can be said that eight weeks of HIFT training with and without ginger supplementation can be beneficial in significantly increasing antioxidant enzyme levels and reducing oxidative stress index in men with nonalcoholic fatty liver disease, although a synergistic effect was not observed.

Keywords

Main Subjects

References

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Research in Exercise Nutrition
Volume 3, Issue 3
May 2024
Pages 12-1

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History

  • Receive Date: 10 February 2025
  • Revise Date: 08 March 2025
  • Accept Date: 08 March 2025
  • First Publish Date: 08 March 2025

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