نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I
نویسندگان
گروه علوم ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران.
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
The aim was to investigate the impact of eight weeks of aerobic training with and without arginine supplementation on hunger, meal satiety, and the expression of miR-200a-3p and miR-103a-3p genes in plasma of obese women
48 inactive volunteer women (age 57.41 ± 4.69 years and body mass index 34.09 ± 1.09 kg/m²) were randomized into aerobic exercise and placebo, aerobic exercise and arginine supplementation, or arginine supplementation and placebo (without exercise) groups. They participated in an eight-week aerobic exercise program, consisting of treadmill running with a GTX test at 60% of the heart rate at exhaustion, completing 500 calories (three days a week). They also consumed arginine at a dose of 0.07 grams per kilogram of body weight daily. One-way analysis of variance and paired t-test were used to analyze the data.
Results: The expression of both miR-200a-3p and miR-103a-3p genes was significantly reduced in all three groups (P<0.05). In the arginine supplementation group, there was no significant reduction in waist circumference, body weight, and time to exhaustion (P>0.05). In the aerobic exercise plus arginine supplementation group, all indices, including gene expression, waist circumference, body weight, hunger, meal satiety, and time to exhaustion, were significantly improved (P<0.05). Additionally, in the aerobic exercise group, there was no significant decrease in hunger and meal satiety (P>0.05).
Conclusion: Aerobic exercise and arginine supplementation reduce the expression of miR-200a-3p and miR-103a-3p genes as well as hunger sensation. Additionally, they improve obesity indices (waist circumference and body weight), immediate satiety quotient, and time to exhaustion.
کلیدواژهها [English]
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